| Date | Opponent | Score |
|---|---|---|
| Sep 1, 2000 | Dewey | W, 21-0 |
| Sep 8, 2000 | at Vinita | L, 14-46 |
| Sep 15, 2000 | at Jay | L, 7-20 |
| Sep 22, 2000 | at Chelsea | W, 28-10 |
| Sep 29, 2000 | Adair | W, 27-0 |
| Oct 6, 2000 | at Salina | L, 19-37 |
| Oct 13, 2000 | Colcord | L, 21-28 |
| Oct 19, 2000 | at Chouteau | W, 34-15 |
| Oct 27, 2000 | Metro Christian | L, 15-31 |
| Nov 3, 2000 | at Caney Valley | W, 50-0 |
| Nov 10, 2000 | Perry* | L, 12-42 |
| * - Playoffs | ||